There are a few ways to run VBscript. I will attempt to outline some methods briefly.
Firstly, VBScript is generally saved into a file with extension .vbs (eg MyScript.vbs), some other file types are .vbe, .wsf, .wsc, but I primarily deal with .vbs. VBScript does not need to be compiled, so these files can be human read.
My primary method of running or executing VBScript is to open a command prompt, then to type cscript then the name of the script. If the script file is in a different folder (eg c:\Temp) you would need to type cscript C:\Temp\MyScript.vbs
You can use wscript rather than cscript in a command prompt, but the main difference is that if there are any dialogue boxes or output, cscript will write this into the command window, but wscript will create a dialogue box which you probably need to click for the script to continue. I generally write scripts that shouldn’t need any interaction, so cscript is better for me.
Another option is to double click on the script in explorer. This will run wscript and use that directory as the working directory. This is great for scripts where you want interaction, but it means you can’t easily do something tricky like provide parameters.
Hope this brief overview helps!